Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Rhys Ifans Mycroft Holmes Guest Star Ralph Brown Tim Sherrington Guest Star Emily Bergl Marion West Guest Star Jim Norton Sir James Walter Guest Star Jordan Gelber M.E. Hawes Guest Star Tony Sheldon British Doctor Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer Craig Sweeny Executive Producer Bob Goodman Writer Guy Ferland Director