Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Desmond Harrington Michael Actor Liza J. Bennett Hannah Gregson Guest Star Parminder Nagra Special Agent Mallick Guest Star Dan Butler Denny Mulgrew Guest Star Edward James Hyland Curtis Jenkins Guest Star Jenna Stern Angela Donnely Guest Star Stephen Conrad Moore FBI Suit 1 Guest Star Lawrence Clayton Manager Guest Star Brian Gonzales Louie Guest Star Julian Nicholas Elfer Lord St. Simon Guest Star Robert Doherty Executive Producer, Writer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer Christine Moore Director