Treat Williams Dr. Andrew Brown Actor Gregory Smith Ephram Brown Actor Emily VanCamp Amy Abbott Actor Debra Mooney Edna Abbott Actor John Beasley Irv Harper Actor Vivien Cardone Delia Brown Actor Chris Pratt Bright Abbott Actor Stephanie Niznik Nina Feeney Actor Merrilyn Gann Rose Abbott Actor Tom Amandes Dr. Harold Abbott Actor Scott Wolf Dr. Jake Hartman Actor Anne Heche Actor Shane Haboucha Guest Star Sarah Drew Hannah Rogers Guest Star Jimmy Bennett Guest Star Greg Berlanti Executive Producer Mickey Liddell Executive Producer Barbie Kligman Writer Matt Shakman Director