John Francis Daley Sam Weir Actor Linda Cardellini Lindsay Weir Actor Samm Levine Neal Schweiber Actor Martin Starr Bill Haverchuck Actor James Franco Daniel Desario Actor Jason Segel Nick Andopolis Actor Seth Rogen Ken Miller Actor Joe Flaherty Harold Weir Actor Becky Ann Baker Jean Weir Actor Busy Philipps Kim Kelly Guest Star Ann Dowd Cookie Kelly Guest Star Jack Conley Kim Kelly's Stepfather Guest Star Sarah Hagan Millie Kentner Guest Star Rashida Jones Karen Scarfolli Guest Star Steve Bannos Frank Kowchevski Guest Star Judd Apatow Executive Producer Jake Kasdan Director Paul Feig Writer, Producer