John Francis Daley Sam Weir Actor Linda Cardellini Lindsay Weir Actor Samm Levine Neal Schweiber Actor Martin Starr Bill Haverchuck Actor James Franco Daniel Desario Actor Jason Segel Nick Andopolis Actor Seth Rogen Ken Miller Actor Joe Flaherty Harold Weir Actor Becky Ann Baker Jean Weir Actor Busy Philipps Kim Kelly Guest Star Natasha Melnick Cindy Sanders Guest Star Jessica Campbell Amy Andrews Guest Star Dave Allen Jeff Rosso Guest Star JoAnna Garcia Swisher Vicki Appleby Guest Star Stephen Lea Sheppard Harris Trinsky Guest Star Ben Stiller Agent Meara Guest Star Judd Apatow Executive Producer Jake Kasdan Director Paul Feig Writer, Producer