James Arness Marshal Matt Dillion Actor Milburn Stone Dr. Galen "Doc" Adams Actor Amanda Blake Kitty Russell Actor Ken Curtis Festus Guest Star Burt Reynolds Quint Guest Star James Nusser Louis Pheeters Guest Star Roy Roberts Mr. Botkin Guest Star Glenn Strange Sam Actor Howard Culver Clerk Guest Star Denver Pyle Caleb Guest Star L.Q. Jones Jim Brady Guest Star Dennis Cross Three Hand Guest Star Royal Dano Praylie Guest Star Michael Forest Bob Sullins Guest Star Willard Sage Mel Billings Guest Star Elisha Cook Jr. George Guest Star Anne Barton Mrs. Boake Guest Star Hank Patterson Hank the stableman Guest Star Roy Barcroft Mr. Botkin Guest Star Fred Coby Wagoneer Guest Star Philip Leacock Producer Norman MacDonnell Producer John Meston Writer Les Crutchfield Writer Kathleen Hite Writer Mark Rydell Director Calvin Clements Sr. Writer Clyde Ware Writer Harry Kronman Writer George Eckstein Writer Will Corry Writer Robert Lewin Writer Gustave Field Writer Harry Harris Director Andrew V. McLaglen Director Michael O'Herlihy Director Vincent McEveety Director Joseph H. Lewis Director Joseph Sargent Director Richard C. Sarafian Director