Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Kal Penn Dr. Lawrence Kutner Actor Olivia Wilde Thirteen, Dr. Remy Hadley Actor Diane Baker Blythe House Guest Star R. Lee Ermey John House Guest Star Samantha Quan Nicole Guest Star Scott Paulin Bob Guest Star Christine Healy Janice Guest Star Jack Conley Sheriff Costello Guest Star Ho-Kwan Tse Fang Dong Wen Guest Star Raymond Ma Wu Zheng Guest Star Esther Kwan Wu An Lan Guest Star Jonathan Palmer Minister Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer David Platt Director Doris Egan Writer David Foster Writer