Damon Wayans Roger Murtaugh Actor Clayne Crawford Martin Riggs Actor Jordana Brewster Dr. Maureen "Mo" Cahill Actor Kevin Rahm Captain Brooks Avery Actor Keesha Sharp Trish Murtaugh Actor Johnathan Fernandez Scorsese Actor Dante Brown Roger Murtaugh Jr. Actor Chandler Kinney Riana Murtaugh Actor Michelle Mitchenor Guest Star Jason Derulo Guest Star Kristoffer Polaha Guest Star Jason Rodriguez Guest Star Silvia Busuioc Guest Star Kwame Patterson Guest Star Rick Ravanello Guest Star Golden Brooks Guest Star Matt Miller Executive Producer McG Executive Producer Dan Lin Executive Producer Jennifer Gwartz Executive Producer