Lucas Till Angus "Mac" MacGyver Actor George Eads Jack Dalton Actor Justin Hires Wilt Bozer Actor Tristin Mays Riley Davis Actor Meredith Eaton Matty Webber Actor Isabel Lucas Samantha Cage Actor William Baldwin Elwood Guest Star Reign Edwards Leanna Martin Guest Star Luna Lauren Velez Cassandra Glover Guest Star Amy Okuda Zoe Guest Star Domenick Lombardozzi Gunman Guest Star Kyle Kennedy Coast Guard Admiral Guest Star Jeff Sprauve Russ-Student Guest Star Kate Bond Jill-Tech Guest Star Paul Downs Colaizzo Executive Producer Brett Mahoney Executive Producer David Von Ancken Executive Producer Henry Winkler Executive Producer Lee David Zlotoff Executive Producer Craig S O'Neill Executive Producer Brian F. Durkin Writer Andrew Karlsruher Writer Tawnia McKiernan Director