Chad Michael Murray Lucas Scott Actor James Lafferty Nathan Scott Actor Hilarie Burton Peyton Sawyer Actor Bethany Joy Lenz Haley James Scott Actor Paul Johansson Dan Scott Actor, Director Sophia Bush Brooke Davis Actor Barbara Alyn Woods Deb Scott Actor Lee Norris Marvin 'Mouth' McFadden Actor Barry Corbin Coach Brian "Whitey" Durham Actor Craig Sheffer Keith Scott Actor Moira Kelly Karen Roe Actor Kevin Kilner Guest Star Michael Trucco Guest Star Tyler Hilton Guest Star Antwon Tanner Guest Star Brett Claywell Guest Star Danneel Ackles Guest Star Sheryl Lee Guest Star Bryan Greenberg Guest Star Bevin Prince Guest Star Mark Schwahn Executive Producer, Writer Michael Tollin Executive Producer Brian Robbins Executive Producer Joe Davola Executive Producer John Asher Director Gregory Prange Director Thomas J. Wright Director Terrence Coli Writer James Stoteraux Writer Janice Cooke Director Billy Dickson Director R. Lee Fleming Jr. Writer Stacy Rukeyser Writer Mike Herro Writer Chad Fiveash Writer William H. Brown Writer Anna Lotto Writer David Strauss Writer