Kate Walsh Dr. Addison Montgomery Actor Tim Daly Dr. Pete Wilder Actor Audra McDonald Dr. Naomi Bennett Actor Paul Adelstein Dr. Cooper Freedman Actor Kadee Strickland Dr. Charlotte King Actor Christopher Lowell William "Dell" Parker Actor Taye Diggs Dr. Sam Bennett Actor Amy Brenneman Dr. Violet Turner Actor Clea Duvall Natasha Guest Star Brian Benben Dr. Sheldon Wallace Guest Star James Morrison William White Guest Star Christina Chang Dr. Vanessa Hoyt Guest Star Emily Rose Elisha Guest Star Aldis Hodge Esau Ajawke Guest Star Adam Godley Henry Guest Star Elizabeth Sampson May Guest Star Preston James Hillier Agent Jones Guest Star Christina j Chang Flight Attendant Guest Star Ara Anton E.R. Doctor Guest Star Shonda Rhimes Executive Producer Betsy Beers Executive Producer Marti Noxon Executive Producer Mark Gordon Executive Producer Mark Tinker Executive Producer, Director Jon Cowan Executive Producer Robert Rovner Executive Producer Ayanna Floyd Writer