Emma Roberts Chanel Oberlin Actor Jamie Lee Curtis Dean Cathy Munsch Actor Lea Michele Hester Actor Abigail Breslin Chanel No. 5 Actor Billie Lourd Chanel No. 3 Actor Keke Palmer Zayday Williams Actor John Stamos Dr. Brock Holt Actor Taylor Lautner Dr. Cassidy Cascade Actor Kirstie Alley Nurse Hoffel Actor James Earl Chamberlain Jackson Actor Brooke Shields Guest Star Trilby Glover Guest Star Andy Erikson Guest Star Clayton Farris Guest Star Ajay Mehta Guest Star Tory N. Thompson Guest Star David Aaron Guest Star Ryan Murphy Executive Producer Brad Falchuk Executive Producer Ian Brennan Executive Producer Alexis Martin Woodall Executive Producer