Tom Welling Clark Kent Actor Kristin Kreuk Lana Lang Actor Michael Rosenbaum Lex Luthor Actor Sam Jones III Pete Ross Actor Allison Mack Chloe Sullivan Actor John Schneider Jonathan Kent Actor Annette O'Toole Martha Kent Actor John Glover Lionel Luthor Actor Ian Somerhalder Adam Knight Guest Star Jonathan Taylor Thomas Ian Randall Guest Star Jesse Metcalfe Van McNulty Guest Star Lorena Gale Dr. Claire Foster Guest Star Shawn Ashmore Eric Summers Guest Star Ron Selmour Connelly Guest Star Elias Toufexis Luke Guest Star Paul Moniz De Sa Orderly Guest Star Gina Doty Pharmacy Nurse Guest Star R. David Stephens Doctor Guest Star Jennifer Kitchen Physical Therapist Guest Star Leanna Nash Nurse Guest Star Julius Chapple Lionel Luthor's Employee Guest Star Alfred Gough Executive Producer Miles Millar Executive Producer Greg Beeman Director Todd Slavkin Writer Darren Swimmer Writer