Melissa Benoist Kara Danvers, Supergirl Actor Chyler Leigh Alex Danvers Actor Mehcad Brooks James Olsen Actor David Harewood Hank Henshaw Actor Jeremy Jordan Winslow "Winn" Schott Actor Chris Wood Mon-El Actor Katie McGrath Lena Luthor Actor Odette Annable Samantha Arias, Reign Actor Nesta Cooper Tanya Guest Star Carl Lumbly M'yrnn J'onzz Guest Star Chad Lowe Thomas Coville Guest Star Emma Tremblay Ruby Arias Guest Star Sofia Vassilieva Olivia Guest Star Greg Berlanti Executive Producer Allison Adler Executive Producer Andrew Kreisberg Executive Producer Sarah Schechter Executive Producer Mairzee Almas Director Paula Yoo Writer Eric Carrasco Writer