Melissa Benoist Kara Danvers, Supergirl Actor Chyler Leigh Alex Danvers Actor Mehcad Brooks James Olsen Actor David Harewood Hank Henshaw Actor Jeremy Jordan Winslow "Winn" Schott Actor Chris Wood Mon-El Actor Katie McGrath Lena Luthor Actor Odette Annable Samantha Arias, Reign Actor Carl Lumbly M'yrnn J'onzz Guest Star Erica Durance Alura Zor-El Guest Star Betty Buckley Patricia Arias Guest Star Chad Lowe Thomas Coville Guest Star Jesse Rath Querl Dox, Brainiac-5 Guest Star Greg Berlanti Executive Producer Allison Adler Executive Producer Andrew Kreisberg Executive Producer Sarah Schechter Executive Producer Jesse Warn Director Robert Rovner Writer Jessica Queller Writer