Johnny Galecki Leonard Hofstadter Actor Jim Parsons Sheldon Cooper Actor Kaley Cuoco Penny Actor Simon Helberg Howard Wolowitz Actor Kunal Nayyar Raj Koothrappali Actor Mayim Bialik Amy Farrah Fowler Actor Melissa Rauch Bernadette Rostenkowski Actor Kevin Sussman Stuart Guest Star Keith Carradine Wyatt Guest Star Lauren Lapkus Denise Guest Star Rati Gupta Anu Guest Star Matt Knudsen Waiter Guest Star Chuck Lorre Executive Producer, Writer Bill Prady Executive Producer Steven Molaro Executive Producer Tara Hernandez Writer Adam Faberman Writer Steve Holland Writer Maria Ferrari Writer Anthony Del Broccolo Writer Mark Cendrowski Director