Eric Ellis Overmyer Creator, Executive Producer David Simon Creator, Executive Producer, Writer Khandi Alexander LaDonna Batiste-Williams Actor Rob Brown Delmond Lambreaux Actor Kim Dickens Janette Desautel Actor Michiel Huisman Sonny Actor Melissa Leo Toni Bernette Actor Lucia Micarelli Annie Actor Clarke Peters Albert Lambreaux Actor Wendell Pierce Antoine Batiste Actor Steve Zahn Davis McAlary Actor John Goodman Creighton Bernette Actor Davi Jay Robinette Guest Star India Ennenga Sofia Bernette Actor Phyllis Montana-LeBlanc Desiree Guest Star Ntare Guma Mbaho Mwine Jacques Vaz Guest Star Dr. John Himself Guest Star Tom McDermott Himself Guest Star Trombone Shorty Himself Guest Star Bruce Barnes Guest Star Venida Evans Mrs. Brooks Guest Star Lance E. Nichols Larry Williams Guest Star Marc John Jefferies Darius Guest Star Tarra Riggs Lula Prichett Guest Star Ameer Baraka Lorenzo Guest Star Vernel Bagneris Judge Bernard Williams Guest Star Calvin Bickham Guest Star Carl J. Walker Donald Guest Star Danny Ladmirault Guest Star John Fohl Guest Star Antonino Paone Harvey Guest Star Fetia Rogers Guest Star Thomas "Bo" Bryson Guest Star Tim Bellow Riley Guest Star Jen Kober Andrea Cazayoux Guest Star Vanessa Cloke Wine Store Clerk Guest Star Henry Griffin Guest Star Gregory Williams Officer No. 1 Guest Star Alana Eastern Guest Star Steve McHugh Chef Guest Star Louis Herthum Sheriff Don Babineaux Guest Star Lawrence P. Beron Tour Bus Driver Guest Star Otto DeJean George Cotrell Guest Star Glenn Robin Party Guest Guest Star Fred Johnson Guest Star Big Chief Monk Boudreaux Himself Guest Star Darryl Montana Himself Guest Star Cherice Harrison-Nelson Guest Star Stafford Agee Guest Star Alonzo Bowens Guest Star Clarence Dalcour Guest Star Irving "Honey" Banister Jr. Guest Star Jeff Tyson Guest Star Ken Williams Guest Star Herman V. Ernest Guest Star Darryle Johnson Guest Star Annette Doucet Sharpe Guest Star Christi Barlow Neighbor Guest Star Emily D. Haley Woman at Bar Guest Star Jacquelyn Twodat Jackson Club Goer Guest Star Karen Kaia Livers Mrs. Robinette Guest Star Steve Rally Ny Patron Guest Star Jaz Sawyer Mardi Gras Party Man Guest Star Danzel Square Civilian No. 1 Guest Star David Mills Screenwriter, Writer George Pelecanos Writer Lolis Eric Elie Writer Tom Piazza Writer Ernest R. Dickerson Director