Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Emily Osment Mandy Actor Ed Begley Jr. Dr. Linkletter Guest Star Wendie Malick President Hagemeyer Guest Star Katherine Von Till Kimberly Guest Star Eileen Galindo Mrs. Howard Guest Star Jeff Doucette Leslie Guest Star Timothy Davis-Reed Jerry Guest Star Gabriel Burrafato Ken Guest Star Winston Story Nelson Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Steve Holland Writer Nick Bakay Writer Eric Kaplan Writer Jeremy Howe Writer Connor Kilpatrick Writer Alex Reid Director