Osmosis Jones (2001) - Rotten Tomatoes

Osmosis Jones (2001)

TOMATOMETER

AUDIENCE SCORE

Critic Consensus: The animated portion of Osmosis is zippy and fun, but the live-action portion is lethargic.

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Movie Info

Peter Farrelly and Bobby Farrelly, the impish impresarios of gross-out comedy, take their body function-inspired humor to new extremes in this mixture of live action and animation. Bill Murray stars as Frank, a zoo worker suffering from the effects of an unknown malady he contracted after eating an egg contaminated with simian saliva. Unknown to Frank, the inside of his body is actually a city (the City of Frank) teeming with cellular life, where the mysterious illness he's fighting is an invading enemy that must be defeated at all costs. It's up to Osmosis Jones (voice of Chris Rock), a white blood cell cop, and Drix (voice of David Hyde Pierce), a rookie over-the-counter medication, to hunt down and stop a lethal virus (Laurence Fishburne) who's got an inferiority complex. Along the way, the partners visit Frank's runny nostrils (Booger Dam) and a bar called, appropriately enough, the Zit. Osmosis Jones costars Molly Shannon and Chris Elliott, and features the vocal talents of William Shatner, producer Joel Silver, and singer Brandy Norwood. ~ Karl Williams, Rovi

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Cast

Bill Murray
as Frank Detorri
Chris Rock
as Osmosis Jones
William Shatner
as Mayor Phlegmming
Molly Shannon
as Mrs. Boyd
Elena Franklin
as Shane Detorri
Kid Rock
as Kidney Rock
Ron Howard
as Tom Colonic
E. Danny Murphy
as Zookeeper Superintendent
The O'Day Family
as Zoo Visitors & Staff
Maura O'Brien
as Emergency Room Nurse
Marlene Malone
as Zoo Visitors & Staff
Barbara O'Connor
as Zoo Visitors & Staff
Grady O'Connor
as Zoo Visitors & Staff
The Oberholtzer Family
as Science Fair Family
Emily O'Donnell
as Science Fair Contestant
Emily O'Day
as Volcano Gal
Colleen O'Donnell
as Docky's Clamshack
Diana O'Donnell
as Science Fair Contestant
The Madigan Family
as Science Fair Family
Bruce McIntyre
as Pea Soup Staff
Ruth Meyer
as Zoo Visitors & Staff
The Mone Family
as Docky's Clamshack
Brian Mone
as Police Officer
Bob O'Brien
as Zoo Visitors & Staff
Mandy Marsh
as Zoo Visitors & Staff
Jillian Nicewicz
as Docky's Clamshack
Jo Ann Ninewicz
as Docky's Clamshack
The Murphy Family
as Zoo Visitors & Staff
Joe Murphy
as Bikini Gang
The Neville Family
as Zoo Visitors & Staff
Jack McCullough
as Zookeeper
The Urann Family
as Science Fair Family
The Sumner Family
as Science Fair Family
The Tom Beauchene Family
as Zoo Visitors & Staff
The Sullivan Family
as Zoo Visitors & Staff
Morgan Wentzell
as Zoo Visitors & Staff
Jacqueline Wentzell
as Zoo Visitors & Staff
The Winans Family
as Science Fair Family
The Vuilleumier Family
as Science Fair Family
Kathy Wege
as Volcano Lady
Bill Wade
as Pea Soup Staff
Warwick West Side All-Stars
as Zoo Visitors & Staff
Mattie Ostiguy
as Emergency Room Nurse
Jesse Peter
as Laughing Boy
The Perry Family
as Zoo Visitors & Staff
The Peterson Family
as Science Fair Family
Zak Penn
as Emergency Room Doctor #3
The Pelham Family
as Zoo Visitors & Staff
Amy Suhay
as Bikini Gang
Dick Silva
as Science Fair Contestant
The Shields Family
as Zoo Visitors & Staff
The Reske Family
as Zoo Visitors & Staff
The Ripley Family
as Science Fair Family
Dick Rubin
as Bikini Gang
The Roy Family
as Zoo Visitors & Staff
The Woodgate Family
as Zoo Visitors & Staff
Bo Cleary
as Pea Soup Staff
Diane Conrad
as Zoo Visitors & Staff
Judy Conrad
as Zoo Visitors & Staff
Brianna Cabral
as Volcano Gal
The Charpentier Family
as Docky's Clamshack
The Cavallo Family
as Science Fair Family
Nancy Byers
as Pea Soup Supervisor
Buzz Dunn
as Science Fair Contestant
Laura Dunn
as Science Fair Contestant
Silk Willy Dunn
as Oyster Boy
Sean Gildea
as Dreamy Photographer
Allison Barbieri
as Zoo Visitors & Staff
Anna Byers
as Bus Girl #2
Kena Flynn
as Science Fair Contestant
Ben Stein
as The Doctor
Patricia Guiggey
as Bikini Gang
Rachael Kasner
as Bikini Gang
Zen Gesner
as Emergency Room Doctor #1
The Coughlan Family
as Science Fair Family
Catherine Dunphy
as Volcano Gal
The Krupa Family
as Docky's Clamshack
Tom Barbieri
as Zoo Visitors & Staff
Joel Silver
as The Chief
John Britten
as Zoo Visitors & Staff
Helen Britten
as Zoo Visitors & Staff
Allison Kacmar
as Science Fair Contestant
Heidi Hetzel
as Bikini Gang
Krista-Jean Froand
as Science Fair Contestant
The Kouri Family
as Zoo Visitors & Staff
The Curran Family
as Zoo Visitors & Staff
Sean Fitzgerald
as Police Officer
Kelsey Jordan
as Bus Girl #1
The Bill Beauchene Family
as Science Fair Family
Nicole Brathwaite
as Volcano Gal
Kevin Flynn
as Docky's Clamshack Waiter
Thomas Jordan
as Zoo Visitors & Staff
Jamie Heres
as Zoo Visitors & Staff
Kathryn Frick
as Nurse #1
Jimmy Heres
as Zoo Visitors & Staff
John-Eliot Jordan
as Pea Soup Manager
Bob Fennessey
as Zoo Visitors & Staff
George Kouri
as Bikini Gang
Sidney Bartholomew Jr.
as Zoo Visitors & Staff
The Buechs Family
as Science Fair Family
The Brumley Family
as Science Fair Family
Erica Johnson
as Zoo Visitors & Staff
The Hallowell Family
as Zoo Visitors & Staff
Christina Kacmar
as Science Fair Contestant
Grace Costa
as Emergency Room Nurse
The Dunphy Family
as Zoo Visitors & Staff
The Ferguson Family
as Zoo Visitors & Staff
Maryjane Foy
as Docky's Clamshack
The Brown Family
as Zoo Visitors & Staff
Jackie Flynn
as School Janitor
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Critic Reviews for Osmosis Jones

All Critics (108) | Top Critics (31)

The plot's so much old rote, and the characters have all the personality of protoplasm; but the anthropomorphising of this microcosmic metropolis is wonderfully imaginative, and the dialogue decidedly spiffy.

Full Review… | January 26, 2006
Time Out
Top Critic

Remains stubbornly one-dimensional.

Full Review… | August 20, 2001
Salon.com
Top Critic

It should have been placed in a hazardous waste container, encased in concrete and dumped into the Farrelly brothers' septic tank.

August 14, 2001
Washington Post
Top Critic

The animated sequences in Osmosis Jones are funny and clever and thoroughly entertaining, with plenty of lively imagination on display in the transposition of a 1970s cop movie to the inner workings of the human body.

August 10, 2001
Toronto Star
Top Critic

A very clever, very gross, very funny spoof of the clichéd cop genre.

Full Review… | August 10, 2001
Seattle Times
Top Critic

Isn't a movie so much as a health-class nutrition lecture.

Full Review… | August 10, 2001
San Francisco Chronicle
Top Critic

Audience Reviews for Osmosis Jones

Osmosis Jones follows the story of a man named Frank (Bill Murray) who is invaded by a harmful disease under the name of Thrax (Laurence Fishburne) and its up to two cops, one former white blood cell cop named Jones (Chris Rock) And a new weapon to the force under the name Drix (David Hyde Pierce.) Osmosis Jones is one of those movies that tries to do the thing that Warner Bros was doing with their animation during the late 90s and early 2000s, mixing both the 2-D animation with the live action animated world such as in Space Jam or Looney Tunes Back in Action. This movie though takes a little bit of a bigger, or should I say, smaller approach. This movie rather than being cartoon characters that are full sized and to scale, these cartoon characters are just mere and small and can't be seen by the human eye. The look of the film though is very stylized and gritty, not the human world, but the inside of Frank. The inside of this mans body is beautifully animated and it really does look like what a human body would look like if a utopia was inside of a human. The 3-D animation also blends very well into the 2-D animation and the interesting ideas done with this animation is interesting. For example, when something catches fire, say from Thrax, microscopic little chains appear in the flames to prove the smallness of the flame. I will definitely say this is warner bros animation taking a risk in terms of the darkness and gruesomeness of a lot of scenes in this movie but I won't really spoil those moments for those who haven't seen it. Now onto the comedy. Really this film is just a buddy cop movie in animated and microscopic form, the two who are complete opposites are put together in a situation that wouldn't really demand it but the two end up starting to like each other and start bonding as friends. Same as in all other buddy cop movies so there isn't much to interpretation in seeing something different so its really all the same jokes you'd see in a normal buddy cop movie just animated. Now there are a few good comedic moments mainly involving Drix at this club called "The Zit" (Take a guess why its called that.) And the running gag of freezing this small little germ constantly by accident when they're trying to get information out of him. But overall the comedy really falls flat in terms of really being anything different from any other generic buddy cop movie. The main thing that really saves this movie is the acting and voice acting. This movie has some shockingly good voice acting and live acting from Bill Murray and the people he interacts with. Chris rock is decent as Jones and David HYde Pierce does a good job as Drix, but the two performances that steal the show are William Shatner as the Mayor, and Laurence Fishburne as Thrax. Shatner plays this cocky and ignorant mayor of Franks body who is trying to show that the body is in perfect shape when it really is anything but. My dad pointed out a good little similarity between him and the mayor in "Jaws" and the similarity is almost uncanny. The two are pompous and ignorant, and don't care if someone gets hurt they just care about business and publicity and Shatner does a phenomenally good job in this role. But the role that really steals the whole film is Laurence Fishburne as Thrax, MY GOD!!! Fishburne does a phenomenal job as this scarlet virus and he is the main reason just to see this movie. Being able to burn literally anything with the touch of a finger, Thrax has probably one of the most interesting designs i've seen in an animated film. Fishburne also gives Thrax this sense of cool and slyness to him but he can switch from calm and sinister to being just pure off the wall crazy and hate filled, and this is shown in full bloom in the films climax. I also might as well talk about the live action acting. While the acting isn't spectacular in the live action world, Murray does a good job as Frank and works off the daughter character very well enough to keep the films pace going well. Overall Osmosis Jones may not be the absolute best animated film, but the animation is good, and the film is lead by great voice acting to keep the film going at a steady pace.

Michael Edwards
Michael Edwards

Super Reviewer

½

Osmosis: Yo! You see this badge? You see this gun? You see this gooey, white saccus membranous 'round my personhood?... Well, you dealin' with a white blood cell here! I should be out in the veins, fighting disease, not in the mouth on tartar control.  "He's one cell of a guy." Osmosis Jones is a a clever and unique film from the Farrelly brothers. I still don't really like it though. Yeah, the premise is really cool, but the overall execution of that premise is not. The movie turns into a one joke comedy after the initial awesomeness of the first 20 minutes or so. It didn't seem like the Farrelly's knew how to keep this story flowing and the audience caring. They let an extremely smart and cool idea go wasted because of their need to incorporate as many bodily function, fungus and zit jokes as they could into a an hour and a half running time.  Osmosis is a white blood cell in the body of Frank. Frank is an unhealthy, overweight zookeeper, who is raising his young daughter all by himself after his wife has passed away. The movie follows two story lines. There's the live action storyline with the family dynamics of the father-daughter relationship. Then there's an animated storyline going on inside Frank's body. A virus has just come into his body with the intentions of killing Frank. It's up to Osmosis to take the virus down. He also has to fight all the normal problems that affect cops in cop dramas, such as a mistake a long time ago and a boss that doesn't really believe in him. I like the initial setup for this movie, but it just never gets where it needs to be. The film has a pretty incredible cast. Bill Murray plays Frank, and although it isn't one of his more memorable roles, it's still Bill Murray. Then there's the voice cast with people like Chris Rock, Laurence Fishburne, William Shatner and David Hyde Pierce. All the voice actors really sell their performances and sound perfect for their particular character. This is most notable with Fishburne's role as Thrax, the killer virus. He gives a great voice performance and is perfect for the role. Along with the great cast and the cool premise the movie has some great references throughout. At the end, there are some great uses of Titanic's final scenes. Then there's a band that plays at one point in the movie called Kidney Rock, that has Kid Rock and Joe C singing for it. All these elements should add up to something great and the disappointing part of it is that it doesn't. The film had potential, but it still ended up being a misfire for the Farrelly brothers.

Melvin White
Melvin White

Super Reviewer

Clever, funny, a little too gross, but still is a pretty good animated film, not Bill Murrays funniest role though.

Jim Careter
Jim Careter

Super Reviewer

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