Damon Wayans Roger Murtaugh Actor Clayne Crawford Martin Riggs Actor, Director Kevin Rahm Captain Brooks Avery Actor Jordana Brewster Dr. Maureen "Mo" Cahill Actor Keesha Sharp Trish Murtaugh Actor Johnathan Fernandez Scorsese Actor Michelle Mitchenor Detective Bailey Actor Dante Brown Roger Murtaugh Jr. Actor Chandler Kinney Riana Murtaugh Actor Andrew Creer Zach Bowman Guest Star Rex Linn Nathan Riggs Guest Star Scottie Pippen Self Guest Star Andy Buckley Tom Noble Guest Star Zach McGowan Cody Lewis Guest Star Steven Cox Austin Noble Guest Star Josh Wingate Duke Rawlings Guest Star Matt Miller Executive Producer McG Executive Producer Dan Lin Executive Producer Jennifer Gwartz Executive Producer Steve Boyum Director Omar Madha Director Eric Laneuville Director Salli Richardson-Whitfield Director Maja Vrvilo Director John Behring Director Larry Teng Director Silver Tree Director Nick Copus Director